• Senior Radiochemistry Research Technician

    Location US-MA-Boston
    Job Posted Date 5 months ago(5/24/2018 4:27 PM)
    Job ID
    2018-9331
    Category
    Hidden (24988)
    Type
    full time
    Grade
    18
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

     

    The Molecular Cancer Imaging Facility (MCIF) at Dana-Farber Cancer Institute is positioned to provide international leadership in the development of new molecular imaging probes. This facility is co-localized with our mouse imaging hospital allowing us the capability of testing and using such probes in virtually any clinically relevant cancer model in longitudinal treatment studies. This work can then be translated to clinic to allow physicians to better diagnose and characterize cancer, choose targeted therapies, monitor treatment efficacy, and improve the outcomes of adult and pediatric patients with cancer.

     

    The Dana-Farber’s Molecular Cancer Imaging Facility (MCIF) is seeking outstanding applicants for Senior Radiochemistry Research Technician to support MCIF’s pre-clinical activities.

    The Senior Radiochemistry Research Technician will work in a team setting, take direction from the Senior Scientist and be involved in activities aimed at the synthesis and pre-clinical evaluation of novel imaging and therapeutic radiopharmaceuticals.

     

    This position will be primarily based at our Harbor Campus, 27 Dry Dock Avenue.

    Responsibilities

    • Develop radiolabeling methods for small molecules and biologics
    • Develop chromatographic methods to analyze and purify radiolabeled compounds (HPLC, GC, radio-TLC, et al.) 
    • Develop formulations suitable for use in animal and human studies
    • Conduct in vitro assays to evaluate and optimize stability of radiolabeled compounds
    • Translate radiolabeling methods to synthesis units and produce compounds for pre-studies
    • Aseptically prepare radiolabeled products for studies
    • Conduct quality control testing on pre-clinical products
    • Maintain clear and accurate records
    • Following standard operating procedures for pre-clinical and clinical activities
    • Interpret data, recognize aberrant results and propose explanations and next steps
    • Summarize data for reports, patents, and presentations
    • Provide as-needed support to other areas of MCIF including aseptic production, cyclotron operations, materials control, and GMP cleanroom operations (environmental monitoring, cleaning, etc.)

    Qualifications

    REQUIRED EDUCATION/EXPERIENCE:

    BSc Degree in Chemistry (or related major) with a minimum of 2 - 4 years of related experience.  We will also consider a Master's degree in Chemistry with 0+ years of experience.

     

    REQUIRED SKILLS/KNOWLEDGE:
    Working knowledge of organic and analytical chemistry is essential for this role
    Working knowledge of radiochemistry is preferred
    Experience with automated equipment for synthesis and purification is preferred
    Experience in the production and testing of products for animal and human use is considered an asset
    Ability to work independently and in a team with strong communication skills, including proficiency in English both written and oral
    Demonstrated ability to prioritize multitask and troubleshoot problems
    Demonstrated ability to readily acquire new skills and techniques

     

    At times this position will require a shift starting as early as 4:00 am a few times a week and advanced notice would be given.

     

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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