Research Technician - Wagle Lab

Location US-MA-Boston
Job Posted Date 3 months ago(12/29/2017 11:07 AM)
Job ID
Hidden (24988)
full time


Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.


Our Core Values are:


Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.


Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.


Compassion and respect - For those in our care and for one another.


Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.


The Center for Cancer Precision Medicine (CCPM) is a major institutional priority, being established across Dana-Farber Cancer Institute (DFCI), Brigham & Women’s Hospital (BWH), and the Broad Institute (Broad). The mission of this Center is to catalyze the implementation and innovation of precision cancer medicine and medical science at these institutions. The Center will leverage a multitude of existing and new capabilities for comprehensive genomic characterization, computational analysis, and technology development. It will bring together DFCI and BWH resources to pioneer new approaches for tissue biopsies, with the goal of facilitating the generation and clinical interpretation of tumor molecular data from clinical trials. CCPM will integrate and coordinate various research and clinical disciplines, and establish joint capabilities across BWH, DFCI, and the Broad with the ultimate goal of creating a leading cancer precision medicine research enterprise.


The Wagle laboratory is seeking a research assistant to join our team, performing cutting-edge studies focused on understanding the mechanisms of therapeutic response and resistance in breast cancer.


Our laboratory focuses on translational cancer genomics and precision (or “personalized”) cancer medicine.  The laboratory is based at Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT, and is a member of the DFCI/Broad/BWH Center for Cancer Precision Medicine.  The major goal of the laboratory is to use systematic genomic and molecular characterization of tumor samples from patients with cancer to better understand the molecular determinants of tumorigenesis, characterize mechanisms of therapeutic response and resistance, and identify novel characteristics of tumors that might aid in clinical decision-making.


Specific studies include the biochemical and genetic analyses of cancer cell lines and human tumor specimens as a means to understand mechanisms of response and resistance to therapies in breast cancer and other cancers, and to design and develop novel in vitro and in vivo therapeutic approaches


Specific responsibilities include

  • Designing and performing laboratory experiments
  • Documenting, compiling, and analyzing experimental data 
  • Participating in team meetings for experimental planning
  • Reporting findings in oral and written formats
  • Contributing to the organization of the overall laboratory, including regulatory and safety issues
  • Prepare, order, and maintain stocks of necessary reagents, solutions and supplies



A minimum of a Bachelors Degree or equivalent is required, preferably in the Biological or Biochemical Sciences. 


Prior research experience in cancer biology, biochemistry, molecular biology, or genetics is preferred.  In particular, experience with tissue culture, DNA/RNA purification, PCR amplification, subcloning, or retroviral work is a plus.  The ideal candidate will be comfortable in a team environment, enthusiastic about scientific discovery, have strong communication and interpersonal skills, have excellent organizational skills, and be highly self-motivated to contribute to the discovery of new medicine to impact cancer care.


We are looking for candidates who have at least two years of availability.



This is a full time, 40 hour per week position.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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