• Pre-clinical Animal Technologist

    Location US-MA-Boston
    Job Posted Date 3 months ago(2/1/2018 8:13 AM)
    Job ID
    2018-9262
    Category
    Hidden (24988)
    Type
    full time
    Grade
    18
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

     

    Dana-Farber Cancer Institute (DFCI) is seeking a Pre-Clinical Imaging Technologist to support the cancer research activities at the Lurie Family Imaging Center (LFIC). The LFIC is a state-of-the-art 14,000-square foot preclinical imaging facility, equipped with preclinical in vivo imaging capabilities, including Positron Emission Tomography (PET), Single-Photon Emission Computed Tomography (SPECT), Computed Tomography (CT), Ultrasound Imaging (US), Optical Imaging (BLI/ FLI), and image-guided radiation therapy, in order to support investigators with their research programs and studies using innovative and relevant imaging strategies. The interdisciplinary in vivo translational and experimental therapeutics studies conducted at the LFIC are focused on cancer, with an emphasis on in vivo pharmacology and the assessment of novel cancer therapeutics, multimodality imaging of cancer, molecular imaging of pharmacodynamic efficacy, development of novel imaging probes, and target validation. For more information please visit: http://www.lfic.dfci.harvard.edu/

     

    The Pre-Clinical Animal Technologist will integrate with a highly skilled team of preclinical Technologists and Scientists, and report directly to the LFIC Director. He/ she will execute in-vivo imaging mouse studies, as well as conventional animal procedures ((e.g., caliper measurements, clinical scoring) to evaluate experimental cancer therapeutics. He/ she must be able to work in a team environment, contribute intellectually and technically to the setting, and work in compliance with the local, state, federal and regulations and guidelines.

    Responsibilities

     

    Responsibilities

     

    • Assist with the establishment and maintenance of mouse cancer models (e.g. by injection or minor surgery).
    • Perform mouse in vivo animal procedures, including dosing animals by various routes (e.g. oral, intravenous, intraperitoneal, etc…), measuring tumors by calipers, non-invasive imaging (PET, MRI, CT, BLI/FLI, US)
    • Perform efficacy and tolerability testing in mouse cancer models
    • Maintain treatment records and inventory of all pharmaceuticals, equipment and supplies, and help with other administrative tasks.
    • Responsible for maintaining and reporting accurate records, including but not limited to data associated with drug efficacy and tolerability studies, health monitoring reports.
    • Requires a working knowledge of basic computer skills, including word processing, spreadsheets, and other related software.
    • Routine handling, restraint, identification (including ear notching, tagging, tattooing, and toe clipping) and sexing of common laboratory animals. Ability to distinguish various common laboratory animal strains in accordance with standardized genetic nomenclature and phenotype identification.
    • Coordinate and perform mouse imaging studies for cancer research and drug discovery.
    • Will work in collaboration with Scientists and Physicists staff.

     

     

    Mon-Fri, some nights and weekends will be required.

     

    Qualifications

    • A BA/BS in Animal Science or related life science required.
    • Laboratory Animal Technician preferred.
    • 1-2 years of work experience in small animal studies in academia or industry preferred.   
    • Knowledge in animal studies including IP, IV, SQ injections, oral gavage, blood collection, and minor surgical procedures preferred (e.g., renal capsule implants, mammary fat pad implants, prostate implants).   
    • Prior preclinical PET/SPECT/CT, MRI, BLI and ultrasound experience preferred. 
    • Must be organized and meticulous in record keeping. 
    • Ability to communicate and collaborate with members of a multidisciplinary team. 
    • Excellent interpersonal skills are required. 
    • Individual must be able to safely handle, restrain, perform treatments and euthanize laboratory mice as directed. An understanding of mouse breeding colony maintenance required for establishing breeding colony pairs, sexing animals, weaning pups and entering colony data on cage cards and in computer database. 
    • Previous experience working with infectious agents (ABSL-2/3 level) would be helpful but not required.  In-house training will be provided prior to working in ABSL-2/3 areas.


    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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