• Research Fellow

    Location US-MA-Boston
    Job Posted Date 1 year ago(11/14/2018 4:51 PM)
    Job ID
    full time
    Location : Address
    450 Brookline Ave
    Location : City
  • Overview

    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    Our Core Values are:

    Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy.

    Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct.

    Compassion and respect - For those in our care and for one another.

    Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity.




    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    The Center for Cancer Precision Medicine (CCPM) is a major institutional priority, being established across Dana-Farber Cancer Institute (DFCI), Brigham & Women’s Hospital (BWH), and the Broad Institute (Broad). The mission of this Center will be to catalyze the implementation and innovation of precision cancer medicine and medical science at these institutions. The Center will leverage a multitude of existing and new capabilities for comprehensive genomic characterization, computational analysis, and technology development. It will bring together DFCI and BWH resources to pioneer new approaches for tissue biopsies, with the goal of facilitating the generation and clinical interpretation of tumor molecular data from clinical trials. CCPM will integrate and coordinate various research and clinical disciplines, and establish joint capabilities across BWH, DFCI, and the Broad with the ultimate goal of creating a leading cancer precision medicine research enterprise. 


    This project seeks to develop functional signatures of immune responses in tumors to develop a biomarker-based predictive assay for cancer immunotherapies. The CCPM is seeking a Postdoctoral researcher to perform studies focused on understanding the mechanisms of therapeutic response and resistance to immunotherapies in cancer.  The ideal candidate will have extensive experience and publications in the area of cancer immunology. Candidates should have experience in measurement of immune responses, including histology and other techniques.

    S/he will assist develop and implement methods to apply new technologies and approaches that augment cancer precision medicine. A specific focus lies on histological and pathological analysis of tumor tissue for immunological markers. S/he will assist, design and perform systematic or hypothesis-directed studies of tumor and immune cell response to checkpoint inhibitors, and combination studies in animal tumor model that may inform clinical decision-making, resistance mechanisms or treatment response.


    Ph.D in Biological, Chemical or Engineering Sciences.



    Previous experience in the ethical and humane use of animals in laboratory research is also preferred; willingness to work with animals is required. Excellent communication skills (verbal and written) as well as strong interpersonal skills and experience working in a team are required. Must be comfortable summarizing and reporting results to researchers. Demonstrated commitment to exceeding quality standards and providing exceptional services, meticulous attention to detail, practiced documentation skills, and a commitment to producing accurate and high-quality work are required. Awareness of basic safety issues is also required, as well as the ability to follow safety procedures and maintain a safe work environment.The ideal candidate will be motivated, detail- and goal-oriented, and possess excellent organizational skills - including the ability to handle a variety of tasks in a fast-paced environment. The candidate should additionally have strong interpersonal, communication, and analytical skills.




     This is a full time, 40 hour per week position.



    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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