Research Technician - Translational Immunogenomics Lab

Location US-MA-Boston
Job Posted Date 5 months ago(10/4/2017 4:17 PM)
Job ID
Hidden (24988)
full time


The Dana Farber Cancer Institute (DFCI) brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


The Translational Immunogenomics Lab (TIGL) within DFCI uses state-of-the-art genomic technologies to assess the response of the immune system to cancer and therapy. TIGL evaluates the latest developments in the field, implements the optimal methods for the task at hand, and invents methods when current approaches are inadequate. The current focus of TIGL is discovering patient-specific neoantigens, understanding the details and consequences of interactions between neoantigens and T cells, and applying this knowledge to support neoantigen immunization therapy.




A full-time position is available for a highly motivated research technician to join the Translational Immunogenomics Lab (TIGL) team. Work tasks will include:

  • Preparing and sequencing single-cell and bulk RNA sequencing libraries
  • Performing single-cell qPCR assays for RNA expression, genotyping, and splicing variants
  • Generating plasmid constructs for mammalian expression
  • Transfection and retroviral transduction of murine and human cells
  • Performing cellular assays to assess cytokine release and cytotoxicity
  • Preparing reagents and media used in lab experiments
  • Operating and maintaining lab equipment

Training is available in all procedures; some experience in the above techniques is preferred.


We are looking for candidates who have at least two years of availability. The job will provide great exposure to someone who is considering going to graduate school or medical school in the future.  


  • Education and Experience

    • Minimum of B.A./B.S. with experience in molecular biology. Major in biology or chemistry is preferred.
    • Some previous laboratory experience is required.



    • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
    • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
    • Ability to analyze information and use logic to address work-related issues and problems.
    • Must have attention to detail, meticulous record-keeping skills, and be thorough in completing work tasks.
    • Ability to work within a team environment.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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