The Aguirre lab at Dana-Farber Cancer Institute is a basic and translational oncology laboratory with a focus on gastrointestinal cancers, such as pancreatic cancer. We utilize a variety of genomic, functional genetic and molecular biology approaches to identify novel therapeutic strategies in pancreatic cancer and to test these strategies in patient-derived models or genetically engineered mouse models of the disease. We actively collaborate with clinical oncologists, surgeons, pathologists, geneticists and computational biologists to perform multi-disciplinary translational research.
We are in search of a highly motivated and capable Research Technician to join an interdisciplinary effort to identify new drug targets for pancreatic cancer. The position will involve evaluating new therapeutic strategies in patient-derived organoid models of pancreatic cancer. The successful candidate will have a strong interest in cancer biology and therapeutics and will function as part of a multidisciplinary basic science and translational team. Responsibilities will include evaluating pancreatic cancer cell survival upon CRISPR-Cas9 knockout of essential genes, testing therapeutic sensitivity on organoid models, and studying the genetic and phenotypic predictors of therapeutic response.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
PRIMARY DUTIES AND RESPONSIBILITIES:
MINIMUM JOB QUALIFICATIONS AND LEVEL OF COMPLEXITY:
Bachelor’s Degree or Master’s degree is required with a major in biology, biochemistry, genetics or chemistry. 1-2 years or more of prior laboratory experience is strongly desired but not absolutely required. More experienced applicants who have worked for multiple years as a professional scientist or research technician are also encouraged to apply and would be considered at an appropriate level of compensation and benefits. A history of hard work, sound academic achievement and prior success is required. A pattern of stable working relationships and strong references from prior mentors is also required.
KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.