Bioinformatics Engineer II

3 months ago
Job ID
IT/Health IT/Informatics
full time


Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

We are seeking an intelligent, hard-working, and dynamic individual to serve as a R&D Bioinformatics Engineer for a cutting-edge cancer genomics research and clinical program.


Cancer is a disease of the genome; effectively fighting cancer will depend on the successful application of genomics to the understanding, diagnosis, and treatment of cancer. The mission of the Center for Cancer Genome Discovery (CCGD) at Dana-Farber Cancer Institute (DFCI) is to facilitate genome discoveries in human cancer through basic and translational research. CCGD is partnered with PROFILE, a joint effort of DFCI, Brigham and Women’s Hospital (BWH), and Boston Children’s Hospital.  PROFILE employs state-of-the art genomics technology to generate a detailed report of medically actionable genetic alterations in a CLIA-certified laboratory. These cancer genomic profiles are being used to guide patient treatment and/or stratification for clinical trials of novel anticancer agents.


Our Bioinformatics team is an integral part of both CCGD and Profile, for which we provide detailed analyses of genomic data.  We develop novel approaches for the analysis of genomics data in a research context and translate those developments into clinical applications. We are looking to expand our outstanding team with an R&D Bioinformatics Engineer.


The successful candidate will have proven experience delivering high-quality and robust analysis and bioinformatics solutions in a timely manner.  This position will have a key role the team’s R&D efforts and must work closely with the lab team in the design, testing, and validation of new analysis methods. 


  • Deep computational and analytic abilities demonstrated by a top-tier Masters or Ph.D. in the life sciences with significant programming and algorithm development experience or a top-tier Masters or Ph.D. in math, physics, engineering, computer science, or a related field.
  • 1 to 3 years of experience post-degree preferred
  • Proficiency in at least one of Java, Python, or R
  • Experience querying and creating MySQL databases
  • Experience evaluating and developing tools for the analysis of DNAseq or RNAseq
  • Strong scientific background with prior experience in cancer biology and/or genomics
  • Excellent communication and effective problem-solving skills
  • Ability to work independently and prioritize tasks

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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