Associate Director - Center for Cancer Precision Medicine

4 months ago
Job ID
Hidden (24997)
full time


Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.




Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and the Broad Institute


A Center for Cancer Precision Medicine (CCPM) has been established that spans the Dana-Farber Cancer Institute (DFCI), Brigham & Women’s Hospital (BWH), and the Broad Institute (Broad). The mission of this Center is catalyzing the implementation and innovation of precision cancer medicine and medical science at these institutions. To accomplish this mission, the Center leverages a multitude of capabilities for comprehensive genomic characterization, computational analysis, and new technology development; augments DFCI and BWH resources to pioneer new approaches for tissue biopsies, generates and interprets molecular/genetic data; and incorporates ex vivo functional assessment of tumors from clinical trials and “flagship” studies. CCPM has brought together various research and clinical disciplines, and has established joint capabilities across BWH, DFCI, and Broad leading cancer precision medicine research enterprise here at the Dana-Farber Cancer Institute.




The Center for Cancer Precision Medicine seeks a talented and highly motivated Associate Director to help oversee the day-to-day activities of the Center and coordinate all CCPM research and operational activities.  The Associate Director will directly report to the Deputy Director but will work closely with the CCPM faculty leaders (Director, Deputy Director, Director of Computation) to fulfill the scientific and institutional missions of the center.  The Associate Director will have responsibility for overall Center operations and will coordinate the ongoing projects and the implementation of new CCPM projects across Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and the Broad Institute. 



  • Oversee and coordinate research, computational and operational activities across the Center, as well as with CCPM partners and collaborators.
  • Ensure the successful and timely execution and analysis of research projects performed by the Center in partnership with its affiliated investigators. Work with lead project manager to anticipate, identify and resolve project issues on an ongoing basis.
  • Manage and supervise R&D/technology and Center Research Operations staff. Indirectly manage and support computational staff as needed.
  • Oversee technology/assay development and testing, including working with CCPM leadership to identify new technologies, methods, and/or innovations that may accelerate or improve cancer precision medicine and developmental therapeutics and direct pilot studies in high-priority areas
  • Assist with the selection and design of new flagship research projects in cancer precision medicine and therapeutic response/resistance undertaken by CCPM
  • Partner with research scientists and other scientific staff (within and outside CCPM) to conduct validation and/or proof-of-concept experimental studies to evaluate key hypotheses or methodologies linked to clinical genomic data
  • Work closely with affiliated faculty and staff to coordinate projects and activities across multiple laboratories and clinical centers (e.g., DF/BWCC Disease Centers, BWH Departments of Surgery, Pathology, Interventional Radiology, Broad Institute)
  • Serve as the chief interface between the CCPM and academic/industry collaborators for review, design, execution, and reporting of ongoing project activities. Work with CCPM leadership to develop industry partnerships
  • Monitor the quality of CCPM genomic and other molecular data sets and ensure data generation/analysis is prompt and transferred to collaborators as appropriate
  • Author or co-author scientific manuscripts reporting the results of CCPM research in partnership with collaborators
  • Assist with grant writing and progress reports.  Author or co-author scientific manuscripts reporting the results of CCPM research in partnership with collaborators
  • Where appropriate, present research results on behalf of CCPM at scientific meetings and related venues
  • Develop and help maintain a CCPM website and other resources (e.g., information cards for patients enrolled in CCPM studies)


Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


The CCPM Associate Director must fulfill the following requirements:

  • PhD or MD level education; at least 5 years of post degree experience with prior leadership of large research projects.
  • Extensive experience working in laboratories with a concentration in cancer genomics, tumor biology, and developmental therapeutics.
  • Extensive knowledge of research methodologies and emerging technologies encompassing molecular biology (e.g., tumor tissue processing, nucleic acid preparation), single cell analysis, genomics (including analytical principles), cell culture (including ex vivo tumor cell cultivation) and drug resistance mechanisms
  • Demonstrated data analysis experience
  • Highly organized and self-directed - works well in a constantly changing environment
  • Ability to work closely and effectively with a diverse group of individuals—from trainees to senior leaders—in both academics and industry
  • Entrepreneurial attitude and skills, including a willingness to take risks
  • Capable of highly-independent work as well as being a team player and role model
  • Strong organizational, project management and supervisory skills, with the demonstrated ability to develop and manage complex projects in a matrix environment
  • Superior communication skills (written and verbal)
  • Strong attention to detail


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