Senior Research Tech - Belfer Center for Applied Cancer Science

3 months ago
Job ID
Hidden (24988)
full time


Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


Research Associate, in vivo

The Robert and Renée Belfer Center for Applied Cancer Science is an integrative research center within Dana-Farber Cancer Institute. Our mission is to bridge academia, industry and the clinic to enhance and accelerate drug discovery & development. We work with both industry and academic partners. We apply industrial capabilities to cutting edge academic/clinical science. We partner with industry in drug discovery/development & work with industrial partners to delineate the clinical path of their therapies.


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Position Summary: The candidate will be part of project teams focused on identifying novel targets and therapies for cancer drug development. He/ She will contribute hands-on to the execution of both in vivo and ex vivo PD Biomarker studies in mouse models of cancer.


Job Responsibilities

  •       Build of syngeneic, xenograft, PDX and orthotopic mouse cancer models
  •       Tumor measurements by calipers and bioluminescent imaging
  •       Breeding and genotyping of GEMMs
  •       Micro and major surgeries in mice
  •       Mouse handling and agent administration by various routes
  •       Animal health monitoring
  •       Mouse necropsy and tissue collection
  •        Blood sampling by retro-orbital and cardiac puncture methods
  •       Cell culturing techniques and subcutaneous implantation of cell and tumor grafts
  •       Design studies and execute on complex mouse cancer efficacy and pharmacodynamic  studies
  •         Data recording, data analysis, reporting and interpretation
  •        Contribute to overall vivarium organization and IACUC protocols


  • BS/MS in biological sciences or equivalent
  • 2 years research experience in academic and/or pharmaceutical/biotech environment
  • Experience with mammalian cell culture
  • Experience with tissue lysis and biomarker analyses
  • Independent, self-motivated and innovative
  • Excellent written and oral communication skills
  • Outstanding interpersonal and team skills

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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