Bioinformatics Analyst III

9 months ago
Job ID
IT/Health IT/Informatics
full time


Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

We are seeking an intelligent, hard-working, and dynamic individual to serve as computational biologist for a cutting-edge cancer genomics research and clinical program.


Cancer is a disease of the genome; effectively fighting cancer will depend on the successful application of genomics to the understanding, diagnosis, and treatment of cancer. The mission of the Center for Cancer Genome Discovery (CCGD) at Dana-Farber Cancer Institute (DFCI) is to facilitate genome discoveries in human cancer through basic and translational research. CCGD is partnered with PROFILE, a joint effort of DFCI, Brigham and Women’s Hospital (BWH), and Boston Children’s Hospital.  PROFILE employs state-of-the art genomics technology to generate a detailed report of medically actionable genetic alterations in a CLIA-certified laboratory. These cancer genomic profiles are being used to guide patient treatment and/or stratification for clinical trials of novel anticancer agents.

Our Bioinformatics team is an integral part of CCGD and Profile, providing detailed analysis of genomic data.  We develop novel approaches for the analysis of genomics data in a research context and translate those developments into clinical applications. We are looking to expand our outstanding team with a Bioinformatics Analyst.


This exceptional opportunity offers the chance to work at the forefront of translational cancer technologies and applications.   We seek an accomplished scientist with experience in computational and statistical data analysis to develop novel methods for genomic analysis.  Key responsibilities of this position are:

  • Development of novel algorithms for the analysis of genomic alterations in DNA and RNA.
  • Identification and evaluation of existing analysis tools and incorporate these algorithms into analysis
  • Work closely with experimental colleagues to plan, evaluate, and troubleshoot experimental methods.
  • Share computational methods developed by the team with DFCI/BWH colleagues


  • Master's or PhD in bioinformatics, computer science, statistics, and/or the life sciences.  Previous experience in molecular biology, genomics, or cancer biology is ideal.
  • Experience in computer programming for data analysis.
  • Experience performing statistical analysis on large data sets is preferred.
  • Specific technical experience that would be useful includes knowledge of Python, Java, and/or R.
  • Interest and experience in data visualization and data illustration would be useful.
  • Excellent communication and effective problem-solving skills; and ability to interact with multidisciplinary staff in a fast-paced environment. The successful candidate should be able to work independently, prioritize and manage a variety of tasks, and shift priorities rapidly.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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