Dana-Farber Cancer Institute

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Senior Radiochemistry Research Technician

Senior Radiochemistry Research Technician

Job ID 
2017-6194
Location 
US-MA-Boston
Category 
Technician/Technologist
Type 
full time
Grade 
18
Job Posted Date 
3/2/2017

More information about this job

Overview

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Dana-Farber’s Molecular Cancer Imaging Facility (MCIF) is seeking outstanding applicants for Senior Radiochemistry Research Technician to support MCIF’s pre-clinical activities.

 

The Molecular Cancer Imaging Facility at Dana-Farber Cancer Institute is positioned to provide international leadership in the development of new molecular imaging probes. This facility is co-localized with our mouse imaging hospital allowing us the capability of testing and using such probes in virtually any clinically relevant cancer model in longitudinal treatment studies. This work can then be translated to clinic to allow physicians to better diagnose and characterize cancer, choose targeted therapies, monitor treatment efficacy, and improve the outcomes of adult and pediatric patients with cancer.

 

The Senior Radiochemistry Research Technician will work in a team setting, take direction from the Facility’s Scientific Leader and be involved in activities aimed at the synthesis and pre-clinical evaluation of novel imaging and therapeutic radiopharmaceuticals.

 

This position will be primarily based at our Harbor Campus, 27 Dry Dock Avenue.

Responsibilities

  • Develop radiolabeling methods for small molecules and biologics
  • Develop chromatographic methods to analyze and purify radiolabeled compounds
  • Develop formulations suitable for use in animal and human studies
  • Conduct in vitro assays to evaluate and optimize stability of radiolabeled compounds
  • Translate radiolabeling methods to synthesis units and produce compounds for pre-studies
  • Aseptically prepare radiolabeled products for studies
  • Conduct quality control testing on pre-clinical products
  • Operate cyclotron to produce radionuclides
  • Maintain clear and accurate records
  • Following standard operating procedures for pre-clinical and clinical activities
  • Interpret data, recognize aberrant results and propose explanations and next steps
  • Summarize data for reports, patents, and presentations
  • Support maintenance of clean room, cyclotron and production facility

 

Qualifications

REQUIRED EDUCATION/EXPERIENCE:

  • BSc Degree in Chemistry with at least 2 - 4 years of related experience

REQUIRED SKILLS/KNOWLEDGE:

  • Working knowledge of organic and analytical chemistry is essential for this role
  • Working knowledge of radiochemistry is preferred
  • Experience with automated equipment for synthesis and purification is preferred
  • Experience in the production and testing of products for animal and human use is considered an asset
  • Ability to work independently and in a team with strong communication skills, including proficiency in English both written and oral
  • Demonstrated ability to prioritize multitask and troubleshoot problems
  • Demonstrated ability to readily acquire new skills and techniques
  • Verbal and written proficiency in English




Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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