Associate Director for the Center for Patient Derived Models

9 months ago
Job ID
full time


Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


The DFCI is seeking an accomplished scientist to fill the role of Associate Director of the new Center for Patient Derived Models (CPDM). The primary goal both for this individual and for this collaborative Center will be to work with investigators at the DFCI to launch projects focused on the creation, characterization, and scientific study of human patient cancer models of all types (cell lines, xenografts, acute cell preparations).


The Center is a collaborative resource that supports investigators who wish to contract with the CPDM to create models from patient samples and the Associate Director will be responsible for coordinating operations to achieve these projects in collaboration with investigators and their staff. Investigators may be basic, translational, or clinical science expertise and the CPDM is especially seeking to support the incorporation of human cancer models in clinical trials of novel therapeutics. The ideal candidate is expected to be highly self-motivated and to have a background in human cancer modeling as well as laboratory management experience. The Associate Director will work closely with the Director to fulfill the scientific and institutional mission of the CPDM.  The Associate Director will have responsibility for the daily operations of the Center and will coordinate the deployment of CPDM resources and technologies across DFCI. Continued engagement with the academic mission including contributions to collaborative publications, attending national meetings, and continuing educational opportunities are also encouraged in this position.



More specifically, he/she will hold the following responsibilities and opportunities:

- Support the Director in setting the scientific and strategic directions as well as the operational priorities for the Center.
- Oversee and manage the daily activities of the CPDM including hiring, training and supervising CPDM staff and purchasing / maintaining equipment. Staff will include other scientists, technicians, clinical research coordinators and bioinformatics analysts.
- Oversee and coordinate the operational activities of the Center’s technical, clinical research coordinators, and bioinformatics groups.
- Anticipate, identify and resolve any project issues on an ongoing basis.
- Work closely with faculty and staff to coordinate efforts, prioritize resources, and implement CPDM collaborations.
- Assist in grant and manuscript preparation and fundraising material development for the Center.
- Develop business plans, strategic plans and partnerships, prepare annual reports, assist with budget management, and give presentations on CPDM progress and science as needed.

- Interface with biopharmaceutical and diagnostic companies to integrate new technologies and projects within the CPDM (e.g. new functional diagnostic platforms, novel cell handling and testing technologies).




The Associate Director will be designated a Research Scientist and as such must fulfill the Dana-Farber requirements for this title.  In addition, the Associate Director must fulfill the following requirements:

PhD, MD, or MD/PhD degree(s) required


             - Five years of lab management experience preferred.

- At least 10 years of experience in laboratory science with at least several years experience creating or working with cancer cell lines, patient derived xenograft models, genomics and/or molecular biology research.

- Experience with range of model methods preferred (organoids, orthotopic PDX, spheroids) as well as models from different organs/lineages (e.g.leukemia, breast, brain tumor models) is preferred.
- Proficiency with basic computer applications (Microsoft word, Excel, PowerPoint, Access Database, etc), and familiarity with genomic technologies applied to model systems.
- High degree of organization and self-motivated; individual must work well in a rapidly evolving research environment. 
- Strong project management and supervisory skills.
- Ability to work closely and effectively with a diverse group of individuals from trainees to senior leaders in both academics and industry.
- Excellent written and oral communication skills.


Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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