Scientist I

US-MA-Boston
1 year ago
Job ID
2016-3892
Category
Laboratory/Research
Type
full time
Grade
45

Overview

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

 

We seek a talented and motivated protein biochemist/enzymologist to join a kinase-focused drug discovery effort at the Dana-Farber Cancer institute.  Successful candidate will work with an interdisciplinary team including medicinal chemists, structural biologists, and cancer biologists to develop kinase inhibitors with novel mechanisms of action (see for example Jia et al., Nature 534(7605):129-32). 

Responsibilities

 

Primary responsibilities will include developing and executing assays for inhibitor discovery and characterization. Experience in protein expression and purification using insect cell/baculovirus systems is highly desired. Experience in X-ray crystallography a plus.

 

 

 

 

 

Keywords or areas:

Enzymology, Kinases, Structural Biology, Cancer, Drug Discovery, Protein Biochemistry

Qualifications

A Ph.D. in a related discipline and directly relevant postdoctoral or industry experience is required. Successful applicant will be appointed to the Research Scientist Track at the Dana-Farber Cancer Institute at a level and salary commensurate with experience.

 

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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