Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The Longwood Center for Structural & Chemical Biology at the Dana-Farber Cancer Institute is seeking a full-time Senior Research Technician who will design & execute experiments and analyze & interpret results for ongoing chemical biology and structural biology research. Primary responsibilities include designing and performing, with the aid of liquid handling robots, invitro assays, including biophysical assays (isothermal titration calorimetry (ITC), fluorescence polarization (FP), time-resolved fluorescence resonance energy transfer (TR-FRET), AlphaLisa or AlphaScreen (AS), and thermal stabilization (TSA/DSF) assays), biochemical assays (ADP-Glo and Rhodamine Deubiquitylating), and crystallization screens (sparse and focused, expansion, or optimization). We are looking for candidates who have at least two years of availability. Additional on the job training will be provided. Ideal candidates are motivated, detailed & goal-oriented and possess excellent organizational, communication, and analytical skills, and have at least two years of availability. This is an opportunity to carry forward projects resulting in presentations and publications such as Cell Chem Bio and Structure.
Design and conduct invitro biochemical, biophysical, and crystallographic experiments using liquid handling robots.
Prepare relevant reagents such as compound and buffer solutions.
Analyze and interpret experimental results, write reports, summaries, proposals, presentations, and other publications.
Develop, modify, and improve standard operating procedures and protocols.
Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
Maintain detailed scientific notebook.
Participate in formal and informal presentations of results to staff.
Monitor laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
Use computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
Clean, maintain, and prepare supplies and work areas.
Master or PhD Degree required with a major in biology or biochemistry preferred.
Experience with invitro assay development.
Excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
Ability to analyze information and use logic to address work-related issues and problems.
Attention to detail and be thorough in completing work tasks.
Ability to work within a team environment.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.