• Research Fellow

    Location US-MA-Boston
    Job Posted Date 1 week ago(10/4/2019 3:10 PM)
    Job ID
    2020-17198
    Category
    Fellowships
    Type
    full time
    Grade
    41
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

     

    We are seeking an intelligent, creative, and collegial post-doctoral research fellow to study mechanisms of immune tolerance and targeted therapy resistance in head and neck cancers using basic and translational approaches. We perform pre-clinical mouse modeling and human translational work towards identifying and targeting genomic and immunologic dependencies to improve patient outcomes. Our group has expertise in carcinogen induced oral cancer models and in performing first in class immune and small molecule therapeutic clinical trials.

     

    Research areas include cancer genome discovery, development of oncogene-inducible and carcinogen-based oral cancer models and analysis of patient derived xenografts and tissues to define biology and therapeutic targeting strategies.

     

    We are a highly collaborative group and interact closely with cancer biologists, clinicians, and computational biologists to comprehensively understand head and neck cancer related phenotypes.

     

     

    Responsibilities

     

    We are seeking an enthusiastic bench-level scientist to join our research team. The major focus of this position will be to perform immunologic studies using mouse oral cancer models and human specimens. These experiments center on defining immunotherapy resistance mechanisms in head and neck cancers.

     

    Specific responsibilities include

    • Processing and analysis of patient-derived tissues
    • Carrying out cell culture and mouse studies
    • Performing laboratory experiments, conducting data analysis and interpreting results
    • Designing experiments and executing protocols
    • Maintaining accurate records, writing reports, and preparing and giving presentations
    • Contributing to the overall laboratory safety, organization and productivity

    Qualifications

     

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

     

    Required Qualifications

    • PhD in molecular biology, immunology or equivalent
    • Enthusiastic, team player, and self-motivated individual
    • Experience with cell culture and immunologic assays including FACS, molecular biology techniques including CRISPR based approaches
    • Excellent written and oral communication skills

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