• Senior Research Technician

    Location US-MA-Boston
    Job Posted Date 3 weeks ago(9/24/2019 10:36 AM)
    Job ID
    2019-17085
    Category
    Research- Laboratory
    Type
    full time
    Grade
    17
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

    The Molecular Cancer Imaging Facility (MCIF) at Dana-Farber Cancer Institute provides international leadership in the discovery and development of new molecular imaging probes. The MCIF facility is adjacent to the Lurie Family Imaging Center which allows us to test and use these novel probes in virtually any clinically relevant cancer model or current imaging modality in longitudinal treatment studies. This work can then be translated to clinic to allow physicians to better diagnose and characterize cancer, choose targeted therapies, monitor treatment efficacy, and improve the outcomes of adult and pediatric patients with cancer.

     

    The Dana-Farber’s Molecular Cancer Imaging Facility (MCIF) is seeking outstanding applicants for a
    Senior Research Technician position that will support MCIF’s radiopharmaceutical drug discovery GMP operations. The technician will work in a team setting, take direction from the Facility Manager and will be involved in activities that support MCIF GMP operations for translation and evaluation of novel imaging and therapeutic radiopharmaceuticals. The Senior Research Technician will perform hands-on, operational related duties to assist in the implementation and maintenance of a compliant Quality System.

    Responsibilities

    • Provide as-needed support to all areas of MCIF GMP operations;
      • Materials control, cyclotron operations, radiochemistry production and quality control,
        aseptic production, and cleanroom operations.
    • Support MCIF GMP operations including cleaning and monitoring of controlled environments.
    • Support MCIF GMP program materials management including receipt, storage, testing, and release of raw materials and components.
    • Support radioactive materials management under DFCI radiation safety office training requirement for handling radioactive materials (will be responsible for shipping and receiving procedures).
    • Support radiochemistry group in application of radiolabeling methods for small molecules and biologics.
    • Support aseptic processing operations to prepare radiolabeled radiopharmaceutical products for imaging studies.
    • Support quality control operations (including testing of radiopharmaceutical products).
    • Maintain clear and accurate records following standard operating procedures for pre-clinical and clinical activities.
    • Interpret data, recognize aberrant results and propose explanations and next steps
    • Summarize data for reports, patents, and presentations

    Qualifications

    • BSc Degree in Chemistry or related health sciences major with a minimum of 2 - 4 years of related experience. 
    • Ability to work independently and in a team with strong communication skills, including proficiency in English both written and oral.
    • Demonstrated ability to readily acquire new skills and techniques.
    • Demonstrated ability to prioritize multitask and troubleshoot problems.
    • Experience with documentation databases including, Word, Excel, and PowerPoint is required.
    • Working knowledge of organic and analytical chemistry is preferred for this role.
    • Experience with automated equipment for controlled environmental monitoring is preferred.
    • Experience in the production and testing of products for animal and human use is preferred.
    • Experience with handling radioactive material is highly preferred.
    • Experience in an FDA-regulated environment with GLP and GMP knowledge is highly preferred.
    • Working knowledge of radiochemistry is an asset.
    • Experience with automated equipment for synthesis and purification is an asset.

    This position will typically occupy day shift hours (8:00am-4:30pm) however, at times the Senior Research Technician will be required to start a shift as early as 4:00 am a few times a week (advanced notice would be given).


    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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