• Computational Biologist II, Pediatric Oncology (Armstrong Lab)

    Location US-MA-Boston
    Job Posted Date 4 months ago(6/27/2019 1:52 PM)
    Job ID
    Research- Laboratory
    full time
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    The Laboratory of Dr. Scott Armstrong, Chairman of the Department of Pediatric Oncology at the Dana-Farber Cancer Institute is seeking a Computational Biologist. The Computational Biologist will interact and collaborate closely with other scientists and computational biologists across the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT with the goal of providing necessary computational support to many ongoing projects.


    Our research focuses on the application of genomic and epigenomic approaches to characterize the mechanisms that control stem cell like properties in leukemia. This information is used to develop new therapeutic approaches for cancers affecting children.


    • Analyze sequencing data, for example from RNAseq and ChIPseq experiments
    • Deploy existing programs and algorithms to evaluate other experimental data generated in our labs (e.g., drug synergy experiments, chemical screens, CRISPR screens)
    • Provide support for basic computational tasks in the lab
    • Document methods for reproducible analysis
    • Participate in projects to design, build, integrate and maintain software to organize and visualize experimental results, including databases and custom user interfaces
    • Report data and analytical methods in oral and written formats
    • Participate in all lab meetings and department meetings at DFCI and Broad Institute


    • Bachelor’s degree required; Master’s Degree or PhD in Computer Science, Bioinformatics or related field preferred, or equivalent relevant experience
    • Experience working in a scientific or medical research setting
    • Familiarity with coding in R, Python or other similar scripting language/statistics-based language
    • Familiarity with SQL or other database query language
    • Effective communication skills
    • Strong organizational techniques, including the ability to handle a variety of tasks in a fast-paced environment


    • Experience in computational biology applications a plus
    • Experience with big data and data summary visualization a plus
    • Experience with pipeline/workflow management frameworks (e.g., Snakemake) a plus

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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