• Research Technician - Nikhil Wagle Lab

    Location US-MA-Boston
    Job Posted Date 5 months ago(9/19/2019 12:47 PM)
    Job ID
    Research- Laboratory
    full time
    Location : Address
    450 Brookline Ave
    Location : City
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

    This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.


    The Wagle laboratory is seeking a research assistant to join our team, performing cutting-edge studies focused on understanding the mechanisms of therapeutic response and resistance in breast cancer.


    Our laboratory focuses on translational cancer genomics and precision (or “personalized”) cancer medicine.  The laboratory is based at Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT, and is a member of the DFCI/Broad/BWH Center for Cancer Precision Medicine.  The major goal of the laboratory is to use systematic genomic and molecular characterization of tumor samples from patients with cancer to better understand the molecular determinants of tumorigenesis, characterize mechanisms of therapeutic response and resistance, and identify novel characteristics of tumors that might aid in clinical decision-making.


    Specific studies include the biochemical and genetic analyses of cancer cell lines and human tumor specimens as a means to understand mechanisms of response and resistance to therapies in breast cancer and other cancers, and to design and develop novel in vitro and in vivo therapeutic approaches


    Specific responsibilities include

    • Designing and performing laboratory experiments
    • Documenting, compiling, and analyzing experimental data 
    • Participating in team meetings for experimental planning
    • Reporting findings in oral and written formats
    • Contributing to the organization of the overall laboratory, including regulatory and safety issues
    • Prepare, order, and maintain stocks of necessary reagents, solutions and supplies

    This is a full time, 40 hour per week position


    • Bachelor's Degree required with a major in biology or chemistry preferred. 
    • Prior research experience in cancer biology, biochemistry, molecular biology, or genetics is preferred.  In particular, experience with tissue culture, DNA/RNA purification, PCR amplification, subcloning, or retroviral work is a plus. 
    • Must be comfortable in a team environment, enthusiastic about scientific discovery, have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
    • Ability to analyze information and use logic to address work-related issues and problems.
    • Must have attention to detail and be thorough in completing work tasks.

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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