• Research Technician

    Location US-MA-Boston
    Job Posted Date 7 months ago(3/22/2019 8:58 AM)
    Job ID
    Research- Laboratory
    full time
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

    This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.


    Research Technician – Center for Cancer Evolution at Dana-Farber Cancer Institute


    We are currently seeking a highly motivated and creative scientist to focus on the experimental arm of the CCE. The principal mission of the CCE is to develop and validate mathematical modeling strategies of tumor evolution and treatment response, and eventually utilize these strategies to identify best therapeutic intervention practices. We hope insights gained through the CCE’s research will ultimately allow for improved cancer therapies to improve patients’ lives. The research technician would be principally responsible for data collection to allow for detailed modeling experiments. The responsibilities of this position will include evaluating new therapeutic targets, experimentally validating theoretical models, characterizing cell and cell line properties, performing single cell lineage tracing experiments and analyzing clinical cancer tissue samples along with appropriate documentation of results. The research technician will have the unique opportunity to support tumor modeling studies that will influence our understanding of cancer evolution, as well as participate in the research and design of even better methods if desired.


    Excellent organizational and communication skills, ability to work within a team, flexibility and responsibility are all key for this position. It is anticipated that the successful applicant will pursue advanced doctoral training (MD, PhD or MD/PhD) subsequent to this position.

    Specific duties would include:

    • Culturing of cell line models
    • Injection of cell lines into mice, administering pharmacologic agents to mice, monitoring tumor growth and harvesting and assaying tumors after drug treatment
    • Performing drug testing of cell line models in cell culture.
    • Extraction and analysis of protein, DNA and mRNA from isolated materials
    • evaluation of effects of specific therapies in model system through immunoblotting and other proteomic experiments
    • Extraction and analysis of protein, DNA and mRNA from isolated materials
    • Evaluation of effects of specific therapies in model system through immunoblotting, staining and other proteomic experiments
    • Using general lab equipment
    • Data analysis and recording of results electronically and in a lab notebook
    • Prepare and write up methods and procedures for publications
    • Prepare and maintain database of results
    • Working closely with a scientist who will serve as direct supervisor and mentor
    • Cooperating with a team of experimental and computational scientists
    • Managing ordering and stocking of laboratory supplies
    • Ability to work on a flexible schedule


    Job Qualifications

                We are looking for an enthusiastic and capable individual with a BA or BS degree in a related field. Experience in cell culturing, and with immunoblotting are desirable. In addition to technical and scientific knowledge, this individual should have good organizational, interpersonal, and oral and written communication skills as well as excellent organizational skills, ability to work within a team, flexibility and responsibility are all key for this position



    • Bachelor's Degree required with a major in biology or chemistry preferred. 
    • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
    • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
    • Ability to analyze information and use logic to address work-related issues and problems.
    • Must have attention to detail and be thorough in completing work tasks.
    • Ability to work within a team environment.

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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