• Research Fellow

    Location US-MA-Boston
    Job Posted Date 11 months ago(3/27/2019 10:22 AM)
    Job ID
    full time
    Location : Address
    450 Brookline Ave
    Location : City
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Role and Responsibilities:

    Postdoctoral Fellows will assist the Associate Director for Scientific Operations to develop and fulfill the scientific mission of the Center for Cancer Evolution (CCE). The principal mission of the CCE is to develop and validate mathematical modeling strategies of tumor evolution and treatment response, and eventually utilize these strategies to identify best therapeutic intervention. We will investigate the treatment response of cancer cells and their microenvironment, develop novel mathematical frameworks describing the evolutionary dynamics of tumor progression and treatment response that are parameterized using the experimental systems, and predict and validate optimum intervention strategies that will ultimately be implemented as prospective clinical trials. The CCE is looking for highly motivated and qualified Postdoctoral Fellows to investigate tumor evolution using and creating mathematical models of tumor evolution, heterogeneity, and drug resistance in order to further the understanding of cancer evolution, metastasis formation, and emerging drug resistance. Postdoctoral fellows will have the following responsibilities: 


    • Design and carry out modeling and analyses of datasets.
    • Assist in the design and implementation of databases for the Center.
    • Write code and generate reports for the Center.
    • Work directly with “bench” scientists in analyzing data generated from individual specific and global projects.
    • Prepare reports and give presentations as needed.
    • Interact with the Center’s scientific collaborators and constituents and assist them with their projects.
    • Assist in grant and manuscript preparation for the Center.



    Qualifications for Postdoctoral Fellows are as follows:

    • PhD degree.
    • A strong background in cancer biology and cancer dynamics as well as statistics or applied math is required
    • Background in applied or pure mathematics, statistics, bioinformatics or computational biology; and interest in cancer biology and work experience in probability theory and statistics are preferred.
    • Knowledge of mathematical modeling and evolutionary theory as related to cancer, biostatistics methods and bioinformatics software, and the ability to create novel analysis platforms desired.
    • 3 years experience in statistical computing, preferably in a biological research setting.
    • Familiarity with multiple computer and statistical languages.
    • Ability to work in a team setting.
    • Willingness to work variable hours and days.

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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