• Research Fellow

    Location US-MA-Boston
    Job Posted Date 8 months ago(2/14/2019 9:35 AM)
    Job ID
    2019-13922
    Category
    Fellowships
    Type
    full time
    Grade
    41
  • Overview

     

    The Qi laboratory at the Dana-Farber Cancer Institute is looking for exceptional Postdoctoral Fellows in cancer biology. The Qi lab studies gene regulatory pathways using the emerging discipline of chemical biology. Successful candidates will work with an interdisciplinary team of scientists including medicinal chemists, biochemists, computational biologists, and cancer biologists to establish the mechanistic understanding of targeted protein inhibition in cancer. The successful candidate will perform research that will help make fundamental insights to cancer biology using novel small molecule inhibitors and chemical biology tools.  We expect that novel therapeutics for human clinical investigation will emerge directly from these efforts through academic/industry collaborations.

      

    The postdoctoral fellow will be affiliated with the Department of Cancer Biology at Dana-Farber Cancer Institute, the Department of Medicine at Harvard Medical School and the Broad Institute.

    Responsibilities

    We are seeking an enthusiastic, self-motivated and experienced bench-level scientist to join Qi lab at Dana-Farber Cancer Institute. The major focus of this position will include developing and executing biological assays for inhibitor discovery and characterization while investigating biological role of the targeted proteins in cancer. 

    Specific responsibilities include:

    • Performing cell and molecular biology research including but not limited to tissue culture, genetic manipulation through shRNA/CRISPR, routine protein/RNA/DNA analyses including ChIP-seq and RNA-seq.
    • Conducting protein purification.
    • Performing preclinical translational studies in mouse models of cancer.
    • Performing laboratory experiments and conducting data analysis.
    • Designing experiments and executing protocols.
    • Maintaining accurate records, writing reports, and preparing/giving presentations.

    Qualifications

     

    Qualifications:

    • PhD or MD/PhD in chemical biology, biological sciences or equivalent
    • A strong background in biochemistry, chromatin biology, cancer biology, molecular biology and/or cell biology.
    • Excellent oral and written communication skills.
    • The ability to perform both self-directed and guided research is required.
    • Must demonstrate outstanding ability to work effectively as part of an interdisciplinary team of scientists.
    • Candidates with experience on cancer biology is preferred, but not required.
    • Experience with mouse models of cancer (xenografts, PDXs, GEMMs) is preferred but not required.

     

     

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

     

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

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