• Scientist I - Immunologist

    Location US-MA-Brookline
    Job Posted Date 1 month ago(9/9/2019 4:27 PM)
    Job ID
    Research- Laboratory
    full time
  • Overview

    We are seeking a highly motivated immunologist with a background preferably in tumor immunology to join the translational laboratory of Dr. F. Stephen Hodi at the Dana-Farber Cancer Institute. The successful applicant will lead laboratory based translational efforts in immune therapeutics.  Focus of the work will be the analyses of combinatorial approaches to treatment with anti-angiogenesis targets and immune checkpoint blockade.  This work will involve both in vitro and in vivo modeling to define the roles of angiogenesis and endothelium in immune regulation as well as cross-talk with innate immunity.  Much of the work will involve use of human tissues and model systems as well as analyses of patient samples receiving immune therapies.  Experience with laboratory techniques such as flow cytometry, CyTof, aseptic cell culture, immunoblotting, vector cloning, immune functional assays, ELISA assays, molecular biology and sequencing are preferred. In addition to technical skills, the candidate should be comfortable working independently and collaboratively, creative scientifically, and have strong management and communication skills.


    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Essential duties include but are not limited to:

    • Participate actively in scientific projects related to immunotherapy development and combinatorial approached
    • Design and carry out immunological assays
    • Contribute effectively to weekly discussions focused project development and translation
    • Identify and interact with collaborators to establish best scientific approaches to address the scientific objectives of the study
    • Keep abreast of emerging literature and studies and incorporate this knowledge into the design and analysis of laboratory work
    • Generate data and prepare manuscripts for publications and grant applications


    Education and Experience

    • PhD in Immunology or related sciences highly preferred
    • 0-3+ years post-degree research experience



    • Expert, in-depth knowledge of scientific principles, particularly in immunology
    • Wide-ranging ability to synthesize information from other disciplines
    • Analytical with strong problem-solving skills and the ability to think creatively
    • Demonstrated independent thought and judgment in experimental design and analysis
    • Thorough and detail-oriented with excellent organizational and documentation skills
    • Outstanding oral and written communication skills

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.



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