Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.
We are currently seeking a highly motivated and talented technician to assist with research focusing on identifying novel therapies for treatment of Multiple Myeloma in the Anderson Laboratory at the Jerome Lipper Multiple Myeloma Center and Lebow Institute for Myeloma Therapeutics, the Dana-Farber Cancer Institute. The technician will be an integral member of our research team and will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. Ongoing studies include identification and validation novel molecular drug targets discovered in large cohort of patients based on epigenetic changes (specifically RNA processing), pre-clinical testing of the experimental drugs, and high throughput chemical screens on myeloma patient derived tumor cells and established cell lines.
The candidate will be expected to independently carry out essential research functions in the laboratory that include but are not limited to experience in cell and molecular biology techniques. Specifically, candidate should be well-versed in
1) Maintaining human cell tissue culture;
2) performing cytotoxicity and proliferation assays
3) Western blot analysis (immuno-precipitations and immunoblotting),
4) Transfection/ infection experiments,
5) Flow cytometry assays and analysis (DIVA, FLOWJO) is highly preferred.
6) RNA/DNA extractions, PCR and RT-PCR, growing/purification of plasmids (e.g. fusion constructs).
7) Candidate will carry out small animal studies as needed.
8) General lab organization as well as lab safety issues.
In addition, the candidate will be expected to make presentations at lab meetings as well as write up methods and materials, results, figure legends and constructing figures for grant proposals, progress reports, and manuscripts. The successful applicant may be included as co-author on publications derived from this work.
The successful candidate expected to work flexible hours in order to accommodate experimental needs.
This is an exciting opportunity to work in a cancer research lab that is focused on improving the lives of cancer patients and gain valuable experience. The position is available immediately.
Master or Bachelor of Science required with major in biological sciences and strong background in molecular and cellular biology is preferred. Additional experience in molecular biology, handling of animals, clinical samples or primary tumors, knowledgeable in using bioinformatics tools will be viewed favorably. Proficient computer skills are expected with competency in Word, Excel, power point etc. The applicant must be a self-starter with ability to work well within a team environment, and able to work on his/her own with minimal daily supervision. The individual is expected to be able to multi-task and be well organized, both require good time management skills; pay careful attention to experimental details, and have excellent communication skills. English language reading, writing, and speaking skills required. We are looking for candidates who have research experience in wet lab and can start immediately.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.