Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
We are looking for a self-motivated researcher to join a team of scientists and physician-scientists in the laboratory of Dr. Julie-Aurore Losman, who is appointed at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard. In this critical role, the research associate will function as a member of a multi-disciplinary team of physician scientists and basic scientists working at the Dana-Farber Cancer Institute on a fast-paced, cutting-edge project focused on understanding how cancer cell metabolism shapes chromatin architecture, with the goal of finding novel therapeutic opportunities in hematologic malignancies and solid tumors.
The individual hired should have a solid background in biology and a strong interest in molecular biology. This position would be ideal for those candidates interested in gaining significant experience in biomedical research with the goal of pursuing future graduate studies in medicine and/or research. In order to obtain sufficient training and experience, we are looking for candidates with at least 2 years of availability.
This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.
Our laboratory studies the pathways that give rise to acute myeloid leukemia. We use biochemical assays, cell-based assays, and mouse models of human disease to identify novel tumor suppressors and oncogenes in leukemia, with a focus on understanding the mechanisms by which these genes promote cellular transformation. Our ultimate goal is to identify novel therapeutic targets in acute myeloid leukemia that will have clinical efficacy in patients.
The candidate will be involved in a series of research activities, including building in vitro and in vivo human disease relevant models, experimental design, testing model systems in cellular and molecular assays, including in a high-throughput manner, use of next generation sequencing as well as molecular and cellular biology experiments. The candidate is expected to work largely independently on a daily basis after training and will be closely mentored by a post-doctoral fellow and by Dr. Losman. She/he will interact with and collaborate closely with other biologists, chemists and computational biologists at DFCI and the Broad Institute.
Duties will include:
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.