Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.
The Aguirre lab at Dana-Farber Cancer Institute is a basic and translational oncology laboratory with a focus on gastrointestinal cancers, such as pancreatic cancer. We utilize a variety of genomic, functional genetic and molecular biology approaches to identify novel therapeutic strategies in pancreatic cancer and to test these strategies in patient-derived models or genetically engineered mouse models of the disease. We actively collaborate with clinical oncologists, surgeons, pathologists, geneticists and computational biologists to perform multi-disciplinary translational research.
We are in search of a highly motivated and capable Senior Research Technician to join an interdisciplinary collaborative effort with the Wolpin Lab at Dana-Farber Cancer Institute to generate patient-derived organoid models of pancreatic cancer and to test new therapeutic strategies in these models, with a goal that this approach may inform future clinical management. The successful candidate will have a strong interest in cancer biology and therapeutics and will function as part of a multidisciplinary basic science and translational team. The candidate will work closely with team scientists to generate organoid models from biopsy specimens derived from patients undergoing therapy at Dana-Farber Cancer Institute. Additional responsibilities will include testing therapeutic sensitivity on these organoid models, as well as integrating genomic and transcriptomic data with functional profiling data. The successful candidate will be involved in all aspects of the research from initial processing of the biopsy specimen to organoid culture and drug sensitivity analysis.
PRIMARY DUTIES AND RESPONSIBILITIES:
No direct supervisory responsibilities required but the candidate will be asked to help train additional laboratory members when applicable and will be offered leadership opportunities when appropriate. Candidate will receive general instructions on routine work, detailed instructions on new projects or assignments.
MINIMUM JOB QUALIFICATIONS AND LEVEL OF COMPLEXITY:
Bachelor’s Degree or Masters degree required with a major in biology or chemistry preferred. 2-4 years related work experience. More experienced applicants who have worked for several years as a professional scientist or research technician are also encouraged to apply and would be considered at an appropriate level of compensation and benefits. Developing technical expertise, applies Institute policies and procedures to resolve a variety of issues. Works on problems of moderate scope where analysis of situations or data requires a review of a variety of factors. Exercises judgment within defined procedures and practices to determine appropriate action. Builds productive internal/external working relationships.
KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.