• Cell Processing Spec II

    Location US-MA-Boston
    Job Posted Date 2 weeks ago(6/7/2018 3:38 PM)
    Job ID
    Medical Technologist/Clinical Lab
    full time
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

    Staff members of the Stem Cell Transplant Lab perform a variety of tasks to provide the highest quality products for patients undergoing stem cell transplant and other cellular therapies. Members of this team also provide expertise in the transportation and shipping of cellular products both within the institute as well as to outside facilities. Staff must be competent in aseptic technique, clean room procedures and cGMP requirements for a cell therapy manufacturing laboratory.


    • Process human cellular products by various methods using manual and/or automated aseptic technique.
    • Perform procedures consistently according to standard operating procedures.
    • Accurately and reproducibly generate expected results within established turnaround times.
    • Achieve and maintain competency in routine procedures including:
      • cryopreservation
      • minimal manipulation
      • thawing
      • centrifugation and washing, 
      • controlled-rate freezing, 
      • storage in liquid nitrogen, 
      • labeling and transportation.
    • Review and evaluate test results for acceptability including automated and manual cell counts, viability results, flow cytometry histograms, sterility testing results.
    • Maintain records of procedures and resultant data, both manually and on computer.
    • Enter data correctly in electronic data capture systems.
    • Evaluates/troubleshoot problems related to product analysis and preparation. Appropriately communicates outcomes.
    • Perform environmental monitoring of work area and laboratory.
    • Communicate effectively and professionally with other health care providers involved in the patient's care.
    • Detect, troubleshoot, and correct instrument, reagent, and system failures.
    • Perform preventive and corrective maintenance of equipment and instrumentation. Identify the need for repair or referral as required. 
    • Respond to REES alarm system alerts and document corrective actions appropriately.
    • Maintain a safe and professional working environment.
    • Other duties and procedures as required or assigned.
    • Perform and document QC/QA activities as defined in policies & SOPs.
    • Recognize and report deviations from standard operating procedures.
    • Participate in validation of new instruments & methods. 
    • Examine existing processes and problems and continuously look for process improvement. 
    • Perform competency testing as required. 
    • Work within the cGMP and cGTP guidelines and adhere to all regulatory standards within the Cell Manipulation Core Facility 
    • Performs Specialist I duties independently without continuous supervision or assistance.
    • Competently performs complex processing procedures as a designated subject matter expert.
    • Ability to apply critical decision-making skills during processing when required.
    • Ability to evaluate processing requests for appropriateness. And make recommendations to management about process change?
    • Work with vendors to introduce new technology to the laboratory. 
    • Write and review standard operating procedures. 
    • Design, implement and act as the lead on validation studies and new projects. 
    • Initiate and document corrective actions when required. 
    • Participate in training of new Specialists.
    • Presents new information or educational topics at staff meetings.
    • Actively pursues continuing education opportunities.
    • Active membership in professional organization(s).



    • BS/BA in a Biological Science, Medical Technology or related field. Minimum 3 years experience in a clinical laboratory setting. 
    • Requires ongoing commitment to upgrade job skills.
    • Able to work closely with others and possess solid interpersonal and communication skills.
    • Capable of working in a fast-paced and rapidly changing environment.
    • Effective in an ethically diverse work group. 
    • Capable of producing accurate results within strict time constraints.
    • Willing to accommodate schedule adjustments, as well as off-shift and weekend assignments as workload dictates. 
    • Must possess good judgment, problem solving and analytical skills.
    • Ability to be flexible & adaptable to changing technology. 
    • Attention to detail and interpersonal skills to effectively communicate with staff and physicians. 
    • Good analytical reasoning & ability to perform complex mathematical calculations using scientific notation. 
    • Clinical/research GCP knowledge.
    • Knowledge of lab safety and infection control.
    • Familiarity with operation & performance of basic lab equipment, i.e., centrifuge, microscopes, program freezers, etc.

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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