• Sr. Scientist - Monoclonal Antibody Core

    Location US-MA-Boston
    Job Posted Date 9 months ago(5/11/2018 1:28 PM)
    Job ID
    Hidden (24997)
    full time
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    Position Summary:  The Monoclonal Antibody Core has an opening for a highly motivated and detail oriented individual with a proficiency in antibody production and antibody engineering (Recombinant antibodies).  This includes antibody purification, immunoassay development and a wide variety of molecular biology techniques including bacterial & mammalian expression systems, cloning, sequencing, plasmid propagation, sequence analysis and PCR. 


    This Sr. Scientist will work closely with the Core director to manage the Core and with clients to evaluate and develop project plans for novel antibody generation.  They will be expected to resolve issues and contribute to the overall running and development of the Core facility, demonstrating technical proficiency, scientific creativity, good collaborative skills an ability to work independently and manage others.  Required technical skills include the ability to run immunoassays (ELISA, western blot, flow cytometry and immune-fluorescence), recombinant protein expression (bacterial, insect and mammalian expression systems) FPLC purification (antibodies and recombinant proteins), engineering of recombinant antibodies, Biacore analysis and basic molecular biology techniques (PCR, plasmid propagation, cloning and sequencing).  Experience providing customer service to clients and interacting with CRO’s will be helpful.


    • PhD in immunology, molecular biology or related field.
    • A minimum of  3-4+ years experience making recombinant proteins and antibodies. 
    • 6+ years’ experience post education and one year of management responsibility.
    • Strong background in recombinant antibodies, recombinant protein and purification methodologies.

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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