The Dana Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The Translational Immunogenomics Lab (TIGL) within DFCI uses state-of-the-art genomic technologies to assess the response of the immune system to cancer and therapy. TIGL evaluates the latest developments in the field, implements the optimal methods for the task at hand, and invents methods when current approaches are inadequate. The current focus of TIGL is discovering patient-specific neoantigens, understanding the details and consequences of interactions between neoantigens and T cells, and applying this knowledge to support neoantigen immunization therapy.
A full-time position is available for a highly motivated research technician to examine immune responses in personalized neoantigen based cancer vaccines (Ott, Hu, Keskin et al. Nature 2017), including how cancer cells evade the immune system. The laboratory uses a variety of cutting edge immunological, biochemical, cell biology, and translational approaches to identify new therapeutic targets and develop preclinical models. The technician will be responsible for cell culture and flow cytometry of patient samples collected in the clinical trials, and thus the candidate should have meticulous record keeping and organizational skills. This position will require comfort and ease with cell culture and flow cytometry of patient blood samples. In addition, the candidate will likely learn immunological techniques such as ELISPOT, ELISA assays, basic handling of DNA and RNA, including PCR, and flow cytometry. Training is available in all procedures; some experience in the above techniques is preferred.
We are looking for candidates who have at least two years of availability
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.