• Scientist I - Center for Immuno-Oncology (Immune Assessment Lab)

    Location US-MA-Boston
    Job Posted Date 5 months ago(5/21/2018 11:46 AM)
    Job ID
    Hidden (24997)
    full time
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    The Center for Immuno-Oncology (CIO) is accepting applications for a scientist to coordinate and direct basic and translational biomarker research in immune oncology.


    Qualified individuals will have a MS or PhD with experience in a basic science or translational clinical research laboratory and evidence of academic productivity. Such an individual will work closely with the medical directors of the CIO to develop tissue-based biomarkers to guide patient selection and therapies in the field of cancer immunology. Responsibilities will include overseeing 3 laboratory technicians, reviewing and preparing data, presenting at the weekly group meetings of the CIO and at national meetings, and contributing to high-impact publications. Such an individual oversee the transition of diagnostic tests developed by the CIO into clinical practice at the Center for Advanced Molecular Diagnostics (CAMD) at the Dana-Farber/ Brigham & Women’s Cancer Center.


    The CIO is multi-disciplinary group that includes investigators in basic and clinical research and dedicated to the discovery, development, and application of novel diagnostics and therapies in cancer immunology. A preferred candidate will be comfortable working independently and collaboratively and have strong management skills. Experience with the laboratory techniques used to study primary tissue samples, flow cytometry, gene expression profiling, and next-gen sequencing, is desired.



    • Advanced degree in Immunology, Molecular Biology, or related required.
    • 3-5 years experience post education; one year management responsibility required.

    Level of Skill and Knowledge:


    • Basic tissue culture and molecular biology skills (e.g. qPCR, PCR) required
    • Flow Cytometry and ELISA/Luminex assays knowledge required
    • Mass Cytometry (CyTOF) preferred
    • Advanced knowledge of Flow Cytometry data analysis (e.g. FlowJo, Cytobank) required
    • Theoretical and practical knowledge of Next Generation Sequencing sample preparation workflows and applications and experience Ion Torrent sequencing platform is preferred.
    • Immunology and/or Oncology research experience preferred.
    • Must have excellent personal task management skills and high level of self-motivation
    • Excellent verbal and written communication skills and willingness to collaborate cross-departmentally required.

    Job Complexity:

    • Demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought. Works on problems of diverse scope in which analysis of data requires evaluation of identifiable factors. Exercises judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions.

    Scope of Leadership and Level of Supervision

    • Manages the work efforts of one or more technicians. Is responsible for mentoring. Completes performance appraisals. Works closely with senior managers and directors on unit/lab issues. Wide latitude for decision-making working in conjunction with PIs.


    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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