• Bioinformatics Engineer III

    Location US-MA-Boston
    Job Posted Date 7 months ago(4/4/2018 4:33 PM)
    Job ID
    IT/Health IT/Informatics
    full time
  • Overview

    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    We are seeking an intelligent, hard-working, and dynamic individual to serve as a bioinformatics engineer for a cutting-edge cancer genomics research and clinical program in the bioinformatics platform team as part of the CCGD center and PROFILE program, and the wider Data Science and Bioinformatics group of the Institute.


    Cancer is a disease of the genome; effectively fighting cancer will depend on the successful application of genomics to the understanding, diagnosis, and treatment of cancer. The mission of the Center for Cancer Genome Discovery (CCGD) at Dana-Farber Cancer Institute (DFCI) is to facilitate genome discoveries in human cancer through basic and translational research. CCGD is partnered with PROFILE, a joint effort of DFCI, Brigham and Women’s Hospital (BWH), and Boston Children’s Hospital. PROFILE employs state-of-the art genomics technology to generate a detailed report of medically actionable genetic alterations in a CLIA-certified laboratory. These cancer genomic profiles are being used to guide patient treatment and/or stratification for clinical trials of novel anticancer agents.


    The Bioinformatics Team is looking for a talented and hardworking bioinformatics engineer to help lead and contribute to the work of creating a pipeline platform for use across a variety of applications. 


    This role involves bioinformatics and software development experience.  The bioinformatics engineer would contribute to:


    • Designs and develops software, databases and interfaces for analyzing and manipulating biological data.
    • Draws upon knowledge of biology to improve data mining and management techniques.
    • Collaborates with laboratory researchers to develop high throughput data processing and analysis capability.
    • Adds new software that has been internally developed or imported from outside sources to in-house systems.
    • Provides direct technical and scientific customer support and helps guide, implement and maintain further improvements to bioinformatics software.
    • Works with the entire life science team to diagnose and fix issues with software.
    • Community of practice around tooling and best practice of pipelines
    • Adding to the existing atlas of Dana Farber’s APIs
    • Developing best practice for software, software development lifecycle, and testing



    • Bachelors degree required, MS preferred or PhD in bioinformatics, computer science and/or the life sciences and 3-5 years relevant experience.
    • Familiarity with simple programming using Python or Java, statistical programming using R or related tools, web-development, and database query through SQL.
    • Familiarity with principles of experimental design and modern data analysis paradigms is required.
    • Strong interpersonal skills and ability to effectively interact with all levels of staff and external contacts.
    • Excellent analytical, organizational and time management skills.



    • Experience with working with containers and container technology such as Docker
    • Experience with Web Frameworks (Django, Flask, Spring Boot)
    • Strong experience in automated software testing
    • Experience and knowledge of grid computing systems
    • Experience with common NGS tools and workflows



    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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