• Guinan Lab Research Fellow

    Location US-MA-Brookline
    Job Posted Date 4 weeks ago(3/27/2018 4:10 PM)
    Job ID
    full time
  • Overview


    Exciting opportunity for a post-doctoral fellow to join a translational laboratory studying various aspects of cellular adaptive immunity, especially in relation to T regulatory cell characterization, function and expansion, as well as the effects of costimulatory blockade. We also have an unrelated and more minor focus on TLR related innate immunity. We have a history of successfully conducting basic and preclinical experiments on new biologic agents and translating them into the clinic, and currently collaborate in clinical trials studying the adaptive use of T regulatory cells in allogeneic setings.


    Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


    The ideal candidate will be able and willing to be a full intellectual partner in the ongoing T regulatory research program of this busy and varied lab as well as develop their own project(s) in other aspects of our work. Successful candidates will be expected to take the lead in manuscriot preparation, and conference and data presentations on their projects.



    Must be a post-doctoral fellow. Must have human cellular immunology experience, such as isolation of peripheral blood cells for characterization, purification, and cryopreservation; cell culture; sterile technique; cell-based assays including mixed lymphocyte culture and use of various molecular biology and immunology techniques to asses immune responses. Flow cytometry and cell sorting experience desirable. Prior experience with T cell ummunology in particular a strong plus. Other relevant experience includes multianalyte analysis (e.g. Luminex), ELISA, RT-PCR, genechip and microarray, assay development and adaptation. The ideal candidate will be able to perform their own bioinformatics analyses of these data and will support others in the lab in their analyses of similar data. Experience in murine models is a plus. Other qualities required: Demonstrated strong organizational skills. Reliable, organized, and flexible with ability to handle multiple activities and to reprioritize tasks. Strong written and oral communication skills. Ability to work independently coupled with strengths as a collaborative lab member.


    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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